Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708921 | 0.90 | POLG (0.54) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL6141732 | 0.89 | POLG (0.59) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL9543610 | 0.88 | POLG (0.58) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL6038227 | 0.88 | POLG (0.57) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL10902119 | 0.86 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL25631339 | 0.85 | POLG (0.67) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL3706290 | 0.84 | POLG (0.54) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL16468567 | 0.83 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL22005996 | 0.83 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL14913972 | 0.82 | DUT (0.51) | P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2535423-B1 | Labeling and detection of nucleic acids | LIFE TECHNOLOGIES CORP (US) | 2019-05-15 | — | — | EP | disclosed |
| US-20140336079-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | LIFE TECHNOLOGIES CORP (US) | 2014-11-13 | — | — | US | disclosed |
| EP-2535423-A2 | Labeling and detection of nucleic acids | Life Technologies Corporation (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2224013-B1 | Methods for the determination of telomerase activity using click chemistry | LIFE TECHNOLOGIES CORP (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8114636-B2 | Labeling and detection of nucleic acids | Life Technologies Corporation (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100261181-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | Life Technologies Corporation (US) | 2010-10-14 | — | — | US | disclosed |
| EP-2224013-A1 | Methods for the determination of telomerase activity using click chemistry | Life Technologies Corporation (US) | 2010-09-01 | — | — | EP | disclosed |
| US-20080050731-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | INVITROGEN CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261181-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | RNGTT, ADAR, ALKBH1 | POLG 762/4885POLB 159/4885P2RY2 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.