Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | TLR5 | O60602 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388336 | 0.72 | LIMK1 (0.44) | LIMK1IKBKBCHUKTP53NPC1 | |
| SCHEMBL9869589 | 0.71 | LIMK1 (0.41) | LIMK1IKBKBCHUKHTTCDC7 | |
| SCHEMBL11185693 | 0.68 | KDM4E (0.45) | TRPM8NPC1TSHRRAB9ASLC6A2 | |
| SCHEMBL6264945 | 0.68 | KDM4E (0.50) | LIMK1IKBKBCHUKCDC7DBF4 | |
| SCHEMBL9543679 | 0.65 | LIMK1 (0.41) | LIMK1IKBKBCHUKTP53LMNA | |
| SCHEMBL9869902 | 0.65 | DYRK1A (0.50) | TP53NPC1TSHRHSP90AA1HPGD | |
| SCHEMBL26195627 | 0.64 | BRD4 (0.49) | TP53NPC1TSHRRAB9ATRPV1 | |
| SCHEMBL26766171 | 0.64 | CYP2A6 (0.44) | NPC1TSHRRAB9ATRPV1BRD4 | |
| SCHEMBL15599482 | 0.64 | BRD4 (0.40) | TRPM8NPC1RAB9ATRPV1BRD4 | |
| SCHEMBL11334745 | 0.64 | LIMK1 (0.40) | LIMK1IKBKBCHUKTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |