Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680790 | 0.76 | KDM4E (0.95) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL7913070 | 0.76 | KDM4E (0.75) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL2900693 | 0.76 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL10563413 | 0.75 | KDM4E (0.73) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL7902779 | 0.75 | KDM4E (0.73) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL7903030 | 0.75 | KDM4E (0.73) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL2899565 | 0.75 | KDM4E (0.73) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL2894300 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| Dimethylamine SCHEMBL7910311 | 0.74 | KDM4E (0.68) | ALDH1A1SMN1; SMN2KMT2APPARGNCOR2 | |
| SCHEMBL9590533 | 0.74 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |