Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679511 | 0.84 | KDM4E (0.47) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9679484 | 0.83 | KDM4E (0.46) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9678739 | 0.83 | NPC1 (0.47) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL236467 | 0.80 | RAB9A (0.64) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL238840 | 0.76 | NPC1 (0.64) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL235867 | 0.76 | RAB9A (0.69) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL238576 | 0.75 | NPC1 (0.62) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3262344 | 0.75 | NPC1 (0.61) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2755213 | 0.74 | RAB9A (0.83) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL239039 | 0.74 | NPC1 (0.63) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |