SCHEMBL9544072

SCHEMBL9544072

COC(=O)CNCCc1cccc(OC)c1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.60
CHRM1 P11229 1/20 0.60
CHRM3 P20309 1/20 0.60
KDM4E B2RXH2 3/20 0.60
ALDH1A1 P00352 3/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
TDP1 Q9NUW8 1/20 0.60
MTNR1A P48039 2/20 0.58
MTNR1B P49286 2/20 0.58
NPC1 O15118 1/20 0.57
BCHE P06276 1/20 0.54
CNR1 P21554 1/20 0.53
CYP2D6 P10635 1/20 0.53
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18114970 0.84 CHRM2 (0.77) CHRM2CHRM1CHRM3KDM4EALDH1A1
SCHEMBL7374223 0.84 MEN1 (0.49) ALDH1A1MEN1KMT2ANPC1CNR1
SCHEMBL9542924 0.82 TAAR1 (0.55) ALDH1A1MEN1KMT2ANPC1CNR1
SCHEMBL14432356 0.82 TAAR1 (0.55) KDM4ENPC1CNR1CYP2D6
SCHEMBL9544789 0.81 SMN1; SMN2 (0.61) KDM4EALDH1A1MEN1KMT2ATDP1
SCHEMBL63100 0.81 HDAC1 (0.61) CHRM2CHRM1CHRM3MTNR1AMTNR1B
SCHEMBL3199966 0.81 KDM4E (0.62) CHRM2CHRM1CHRM3KDM4EALDH1A1
SCHEMBL7246282 0.81 CA12 (0.56) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL17143946 0.80 ALDH1A1 (0.74) CHRM2CHRM1CHRM3ALDH1A1TDP1
SCHEMBL9517424 0.80 CHRM2 (0.70) CHRM2CHRM1CHRM3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed