Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544631 | 0.91 | GAA (0.33) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9544689 | 0.87 | ALDH1A1 (0.31) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9544619 | 0.86 | NPSR1 (0.32) | CYP1A2CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL9544317 | 0.85 | NPSR1 (0.35) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9544365 | 0.83 | NPSR1 (0.36) | CYP1A2CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL9545480 | 0.80 | CYP1A2 (0.45) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9545295 | 0.75 | NPSR1 (0.33) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9211418 | 0.75 | NPSR1 (0.36) | CYP1A2CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL9545422 | 0.75 | NPSR1 (0.35) | CYP1A2CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL9545479 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | claimed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |