Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.62 |
| ▸ | CNR2 | P34972 | 10/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544650 | 0.89 | CNR2 (0.66) | CNR1CNR2L3MBTL1SRD5A1SRD5A2 | |
| SCHEMBL9543327 | 0.89 | CNR2 (0.66) | CNR1CNR2L3MBTL1SRD5A1SRD5A2 | |
| SCHEMBL9544612 | 0.87 | CNR1 (0.58) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL9544391 | 0.87 | CNR1 (0.58) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL9545448 | 0.87 | CNR1 (0.58) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL9441241 | 0.87 | CNR1 (0.68) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL9336481 | 0.87 | CNR1 (0.62) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL9543728 | 0.86 | CNR1 (0.59) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL9544332 | 0.86 | CNR1 (0.57) | CNR1CNR2POLBL3MBTL1CREBBP | |
| SCHEMBL7853735 | 0.85 | CNR1 (0.70) | CNR1CNR2POLBL3MBTL1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016996-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |