Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.66 |
| ▸ | CNR1 | P21554 | 6/20 | 0.66 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543327 | 1.00 | CNR2 (0.66) | CNR2CNR1SRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL9544310 | 0.89 | CNR1 (0.62) | CNR2CNR1SRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL9543204 | 0.87 | SRD5A1 (0.70) | CNR2CNR1SRD5A1SRD5A2 | |
| SCHEMBL9544705 | 0.87 | SRD5A1 (0.70) | CNR2CNR1SRD5A1SRD5A2 | |
| SCHEMBL9545397 | 0.87 | SRD5A1 (0.70) | CNR2CNR1SRD5A1SRD5A2 | |
| SCHEMBL9391620 | 0.86 | SRD5A1 (0.61) | CNR2CNR1SRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL9544630 | 0.85 | SRD5A1 (0.71) | CNR2CNR1SRD5A1SRD5A2 | |
| SCHEMBL9544353 | 0.85 | SRD5A1 (0.68) | CNR2CNR1SRD5A1SRD5A2 | |
| SCHEMBL9441098 | 0.84 | SRD5A1 (0.74) | CNR2CNR1SRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL9544642 | 0.83 | SRD5A1 (0.73) | CNR2CNR1SRD5A1SRD5A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016996-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |