Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544456 | 1.00 | ADRB3 (0.43) | ADRB3ADRB1ADRB2GLABACE1 | |
| SCHEMBL9543347 | 0.89 | MEN1 (0.44) | ADRB3ADRB1ADRB2GLABACE1 | |
| SCHEMBL9543338 | 0.89 | MEN1 (0.44) | ADRB3ADRB1ADRB2GLABACE1 | |
| SCHEMBL9545127 | 0.79 | LTB4R2 (0.44) | ADRB3ADRB1ADRB2BACE1FFAR1 | |
| SCHEMBL4462454 | 0.79 | BACE1 (0.43) | ADRB3ADRB1ADRB2BACE1 | |
| SCHEMBL1622477 | 0.79 | BACE1 (0.43) | ADRB3ADRB1ADRB2BACE1 | |
| SCHEMBL4479032 | 0.78 | ADRB3 (0.60) | ADRB3ADRB1ADRB2GLA | |
| SCHEMBL4462538 | 0.78 | ADRB3 (0.60) | ADRB3ADRB1ADRB2GLABACE1 | |
| SCHEMBL4468301 | 0.78 | ADRB3 (0.59) | ADRB3ADRB1ADRB2GLA | |
| SCHEMBL4468296 | 0.78 | ADRB3 (0.59) | ADRB3ADRB1ADRB2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010074-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS BETA-3-ADRENOCEPTOR AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-05-27 | — | — | WO | disclosed |