SCHEMBL9544488

SCHEMBL9544488

N#Cc1ccc2c(n1)-c1ccccc1CCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.43
NPY5R Q15761 5/20 0.42
BCHE P06276 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.38
IKBKB O14920 1/20 0.37
NOS3 P29474 1/20 0.37
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HRH4 Q9H3N8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7268987 0.77 MAOA (0.38) CYP2A6MAOAMAOBKDM4EALDH1A1
SCHEMBL18183649 0.72 KDM4E (0.44) KDM4EALDH1A1TSHRLMNAMAPT
SCHEMBL1509445 0.69 KDM4E (0.57) DRD4NPY5RBCHECYP2A6MAOA
SCHEMBL9368974 0.69 NPY5R (0.60) DRD4NPY5RBCHECYP2A6MAOA
SCHEMBL29740385 0.68 SMN1; SMN2 (0.47) KDM4EALDH1A1TSHRLMNAMAPT
SCHEMBL3900928 0.68 NPY5R (0.53) DRD4NPY5RBCHECYP2A6MAOA
SCHEMBL2960628 0.68 SMN1; SMN2 (0.47) KDM4EALDH1A1TSHRLMNAMAPT
Hydrochloric Acid SCHEMBL9544492 0.68 BCHE (0.42) DRD4NPY5RBCHECYP2A6MAOA
SCHEMBL9541655 0.68 CCR1 (0.47) DRD4NPY5RBCHECYP2A6MAOA
SCHEMBL27918268 0.68 TSHR (0.63) DRD4CYP2A6MAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993014080-A1 BRIDGED HETEROCYCLIC FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-22 WO disclosed