Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27726215 | 0.97 | ACE (0.55) | ACEABCB11CXCR3HDAC8POLB | |
| SCHEMBL27726218 | 0.97 | ACE (0.55) | ACEABCB11CXCR3HDAC8POLB | |
| SCHEMBL27726228 | 0.90 | ACE (0.56) | ACEABCB11HDAC8 | |
| SCHEMBL27726229 | 0.90 | ACE (0.56) | ACEABCB11HDAC8 | |
| SCHEMBL9545015 | 0.90 | ACE (0.56) | ACEABCB11HDAC8 | |
| SCHEMBL9545013 | 0.90 | ACE (0.56) | ACEABCB11HDAC8 | |
| SCHEMBL27726230 | 0.88 | HDAC8 (0.46) | ACECXCR3HDAC8 | |
| SCHEMBL27705683 | 0.88 | HDAC8 (0.46) | ACECXCR3HDAC8 | |
| SCHEMBL9544288 | 0.86 | CXCR3 (0.41) | ACECXCR3HDAC8 | |
| SCHEMBL10739004 | 0.86 | ACE (0.59) | ACEABCB11HDAC8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |