Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019722 | 0.93 | POLB (0.53) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL31019699 | 0.91 | POLB (0.51) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9545487 | 0.87 | CYP1A2 (0.70) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL31019726 | 0.82 | MAPT (0.51) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL27935845 | 0.80 | SMN1; SMN2 (0.54) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9545283 | 0.80 | PTGER4 (0.66) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL13243021 | 0.78 | SMN1; SMN2 (0.49) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9216480 | 0.77 | POLB (0.46) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10091956 | 0.76 | POLB (0.71) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9673200 | 0.75 | POLB (0.60) | POLBCYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |