SCHEMBL9545487

SCHEMBL9545487

Cn1nc(C(F)(F)F)c(C=O)c1Oc1cccc(Cl)c1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.70
CYP2C19 P33261 4/20 0.70
CYP2C9 P11712 3/20 0.70
NPSR1 Q6W5P4 3/20 0.54
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.49
CYP3A4 P08684 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
CYP2D6 P10635 2/20 0.43
GPBAR1 Q8TDU6 1/20 0.41
POLB P06746 1/20 0.41
PTGER4 P35408 3/20 0.39
AR P10275 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9544900 0.87 POLB (0.55) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL3637019 0.83 CYP1A2 (1.00) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL31019735 0.81 CYP1A2 (0.75) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL31019699 0.81 POLB (0.51) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL31019722 0.80 POLB (0.53) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL876769 0.80 LMNA (0.66) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL27935845 0.79 SMN1; SMN2 (0.54) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL13243021 0.77 SMN1; SMN2 (0.49) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL9216835 0.75 NPSR1 (0.57) CYP1A2CYP2C19CYP2C9NPSR1LMNA
SCHEMBL757178 0.74 CYP2C19 (0.48) CYP1A2CYP2C19CYP2C9NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993025535-A1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES RHONE POULENC AGRICULTURE LTD. (GB) 1993-12-23 WO disclosed