Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | THRA | P10827 | 3/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638365 | 0.92 | USP2 (0.50) | DNM1USP2LMNAALDH1A1TSHR | |
| SCHEMBL6547344 | 0.92 | DNM1 (0.52) | DNM1USP2LMNAALDH1A1TSHR | |
| SCHEMBL14520636 | 0.90 | DNM1 (0.50) | DNM1USP2LMNAALDH1A1TSHR | |
| SCHEMBL4149053 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 | |
| SCHEMBL11343070 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 | |
| SCHEMBL4163491 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 | |
| SCHEMBL8431297 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 | |
| SCHEMBL4155109 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 | |
| SCHEMBL6940598 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 | |
| SCHEMBL4139404 | 0.89 | CA12 (0.52) | DNM1ALDH1A1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270310-A | N-aminoalkyl amide inhibitors of protein kinase C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993011758-A1 | N-AMINOALKYL AMIDE INHIBITORS OF PROTEIN KINASE C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |