SCHEMBL9544959

SCHEMBL9544959

N#CCCn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)CNC3=O

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKD3 O94806 7/20 0.71
PRKCG P05129 7/20 0.71
PRKCB P05771 7/20 0.71
PRKCA P17252 7/20 0.71
PRKCH P24723 7/20 0.71
PRKCI P41743 7/20 0.71
PRKCE Q02156 7/20 0.71
PRKCQ Q04759 7/20 0.71
PRKCZ Q05513 7/20 0.71
PRKCD Q05655 7/20 0.71
PRKD1 Q15139 7/20 0.71
MYLK Q15746 3/20 0.71
ROCK2 O75116 3/20 0.71
PRKACA P17612 2/20 0.71
JAK3 P52333 2/20 0.71
PLK4 O00444 1/20 0.71
AURKA O14965 1/20 0.71
PDPK1 O15530 1/20 0.71
JAK2 O60674 1/20 0.71
PAK4 O96013 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4881551 0.96 PRKD3 (0.71) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL30078317 0.96 PRKD3 (0.71) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9201942 0.87 PRKD3 (0.72) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL3267156 0.86 MYLK (0.66) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9203534 0.85 PRKD3 (0.71) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9544836 0.84 MYLK (0.65) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9201746 0.84 PRKD3 (0.70) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9203996 0.84 MYLK (0.68) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9200685 0.83 MYLK (0.72) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL9544946 0.83 PRKD3 (0.64) PRKD3PRKCGPRKCBPRKCAPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993024490-A1 USE OF INDOLOCARBAZOLS IN AIDS TREATMENT Gödecke Aktiengesellschaft (DE) 1993-12-09 WO claimed
WO-1993024490-A1 USE OF INDOLOCARBAZOLS IN AIDS TREATMENT Gödecke Aktiengesellschaft (DE) 1993-12-09 WO disclosed