Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455024 | 0.82 | NPC1 (0.51) | NPC1ALOX5PTPN1PTPN2PTPN11 | |
| SCHEMBL14937365 | 0.79 | ESR1 (0.51) | NPC1ALOX5TSHRPTPN1PTPN2 | |
| SCHEMBL9221026 | 0.78 | SERPINE1 (0.69) | SERPINE1GAAPTPN1PTPN2PTPN11 | |
| SCHEMBL887540 | 0.76 | ADRB2 (0.65) | ADRB2ADRB1ADRB3GAA | |
| SCHEMBL11027636 | 0.76 | KMT2A (0.40) | ALOX5GAATSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL27764131 | 0.76 | NPC1 (0.56) | NPC1ADRB2ADRB1ADRB3ALOX5 | |
| SCHEMBL887514 | 0.75 | ADRB2 (0.64) | NPC1ADRB2ADRB1ADRB3ALOX5 | |
| SCHEMBL35507 | 0.75 | TSHR (0.63) | SERPINE1TSHR | |
| SCHEMBL5183062 | 0.74 | NPC1 (0.39) | NPC1ADRB2ADRB1ADRB3ALOX5 | |
| SCHEMBL11028650 | 0.72 | HTT (0.42) | NPC1ALOX5CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5051354-A | — | — | None | — | — | JP | disclosed |
| JP-H0551354-A | PRODUCTION OF 3,5-DIAMINOBENZOIC GLYCEROL DIMETHACRYLATE ESTER | NIPPON KAYAKU CO LTD | 1993-03-02 | — | — | JP | disclosed |