SCHEMBL9545006

SCHEMBL9545006

C/C=C/Oc1ccc(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
TTR P02766 3/20 0.44
SLC6A2 P23975 3/20 0.44
SLC6A3 Q01959 3/20 0.44
LMNA P02545 2/20 0.44
NR1I2 O75469 1/20 0.44
PGR P06401 1/20 0.44
HSP90AA1 P07900 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
HSPA5 P11021 1/20 0.44
HPGD P15428 1/20 0.44
CBR1 P16152 1/20 0.44
TBXA2R P21731 1/20 0.44
AGTR1 P30556 1/20 0.44
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9545009 1.00 MAPT (0.44) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL1547763 0.83 TTR (0.47) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL9293959 0.79 TDP1 (0.45) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL9293956 0.79 TDP1 (0.45) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL28468173 0.78 ERN1 (0.46) MAPTTTRLMNAHPGDKMT2A
SCHEMBL10887967 0.76 TDP1 (0.45) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL1436760 0.75 TTR (0.47) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL4593314 0.75 TTR (0.49) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL7691212 0.74 TDP1 (0.47) MAPTTTRSLC6A2SLC6A3LMNA
SCHEMBL17513207 0.74 MAPT (0.55) MAPTTTRSLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993016033-A1 CYCLOHEXENONE OXIME ETHERS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-08-19 WO disclosed