Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746894 | 0.98 | TTR (0.47) | TTRTDP1MAPTNR1I2LMNA | |
| SCHEMBL8665449 | 0.83 | TDP1 (0.43) | TTRTDP1MAPTLMNATP53 | |
| SCHEMBL11084246 | 0.79 | TSHR (0.49) | MAPTLMNAHPGDSLC6A2SLC6A3 | |
| SCHEMBL16546178 | 0.79 | TTR (0.53) | TTRTDP1MAPTNR1I2LMNA | |
| SCHEMBL28086712 | 0.79 | TTR (0.46) | TTRTDP1MAPTNR1I2LMNA | |
| SCHEMBL12121021 | 0.79 | ACHE (0.43) | TDP1MAPTLMNAHPGDS1PR4 | |
| SCHEMBL9775676 | 0.79 | SLC6A2 (0.41) | HPGDSLC6A2SLC6A3S1PR4KMT2A | |
| SCHEMBL15834997 | 0.79 | MAPT (0.57) | TTRTDP1MAPTLMNAHPGD | |
| SCHEMBL28832700 | 0.79 | CYP3A4 (0.46) | TDP1MAPTHPGDKMT2ATSHR | |
| SCHEMBL27584712 | 0.79 | SMN1; SMN2 (0.43) | TDP1LMNAHPGDS1PR4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636669-B1 | PYRAZOLE AMIDE COMPOUND AND USE THEREOF AS FUNGICIDE | SINOCHEM CORP (CN) | 2015-10-21 | — | — | EP | claimed |
| US-8614214-B2 | Pyrazole amide compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2013-12-24 | — | — | US | claimed |
| EP-2636669-A1 | PYRAZOLE AMIDE COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2013-09-11 | — | — | EP | claimed |
| US-20130225585-A1 | PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-08-29 | — | — | US | claimed |
| CN-101014585-A | Radically polymerizable sulfur-containing compound and radically polymerizable sulfur-containing polymer | SHOWA DENKO KK (JP) | 2007-08-08 | — | — | CN | claimed |
| CN-1976967-A | Carboxylic acid modified aminoplast crosslinking agent and powder coating compositions | PPG IND OHIO INC (US) | 2007-06-06 | — | — | CN | claimed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | claimed |
| US-4537720-A | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamino)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | claimed |
| CN-112384511-B | Endoparasite depsipeptides | 硕腾服务有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113631548-B | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-108947804-A | A kind of preparation method of chlorobenzene oxycarboxylic acid substance | 山东润博生物科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108947803-A | A kind of preparation method of phenoxy carboxylic acid substance | 山东润博生物科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-104341316-B | Aryl amide derivative of one class two and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2017-07-28 | — | — | CN | disclosed |
| EP-0019760-B1 | ESTERS OF 3-ARYL-5-METHYL-PYRAZOLE-4-CARBOXYLIC ACID, HERBICIDES CONTAINING THEM, PROCESS FOR THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4264495-A | EXHIBITING GOOD COLOFASTNESS AND DYEABILITY ON POLYAMIDES AND OTHER FIBERS | EASTMAN KODAK COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |
| EP-0019760-A1 | Esters of 3-aryl-5-methyl-pyrazole-4-carboxylic acid, herbicides containing them, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4070352-A | COLORFAST, SUBLIMATION AND OZONE RESISTANT BLUE AZO DYES FOR POLYAMIDES | EASTMAN KODAK COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-3932419-A | QUINOLINE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225585-A1 | PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF | BROX, OAT, CAT | TTR 2960/4885TDP1 4236/4885MAPT 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.