Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | CDC25B | P30305 | 4/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751650 | 1.00 | KLK5 (0.54) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL9545042 | 1.00 | KLK5 (0.54) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL24814238 | 1.00 | KLK5 (0.54) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL19614435 | 0.93 | SYK (0.53) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL18558745 | 0.93 | SYK (0.53) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL19614433 | 0.93 | SYK (0.53) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL19853304 | 0.93 | SYK (0.53) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL6387553 | 0.90 | PPARA (0.48) | KLK5PPARASYKMMP9MMP8 | |
| SCHEMBL400186 | 0.90 | PPARA (0.55) | PPARASYKMMP9MMP8CTSS | |
| SCHEMBL1414711 | 0.90 | PPARA (0.55) | PPARASYKMMP9MMP8CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |