SCHEMBL400186

SCHEMBL400186

CC(OCc1ccccc1)C(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.55
PTPN1 P18031 4/20 0.53
CDC25B P30305 4/20 0.53
PTPN2 P17706 2/20 0.53
CDC25A P30304 2/20 0.53
PPARG P37231 2/20 0.50
MMP9 P14780 2/20 0.50
MMP8 P22894 2/20 0.50
APP P05067 2/20 0.49
CTSS P25774 3/20 0.49
SYK P43405 1/20 0.49
ATM Q13315 1/20 0.49
ACE P12821 1/20 0.48
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
CTSK P43235 1/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12018371 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL400187 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL1414710 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL2212074 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL1414711 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL12055688 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL3449019 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
Hydrochloric Acid SCHEMBL28347451 0.99 PPARA (0.54) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL24814238 0.90 KLK5 (0.54) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL9545038 0.90 KLK5 (0.54) PPARAPTPN1CDC25BPTPN2CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
EP-3681875-B1 CYCLIC PEPTIDE ANTIBIOTICS HOFFMANN LA ROCHE (CH) 2026-01-14 EP disclosed
US-12358951-B2 Cyclic peptide antibiotics GENENTECH, INC. (US) 2025-07-15 US disclosed
US-20250074901-A1 NOVEL HETEROARYL COMPOUNDS ANGELINI PHARMA S.P.A. (IT) 2025-03-06 US disclosed
US-20240368096-A1 Fused Heterobicyclic Antiviral Agents ENANTA PHARMACEUTICALS, INC. 2024-11-07 US disclosed
EP-4433453-A1 NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS Icagen, LLC (US) 2024-09-25 EP disclosed
US-12065445-B2 CDK2 inhibitors and methods of using the same CEDILLA THERAPEUTICS, INC. (US) 2024-08-20 US disclosed
US-12053459-B2 CDK2 inhibitors and methods of using the same CEDILLA THERAPEUTICS, INC. (MA) 2024-08-06 US disclosed
US-20240174680-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-05-30 US disclosed
WO-2023091554-A9 NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS ICAGEN, LLC (US) 2024-05-23 WO disclosed
EP-0296574-A2 Cholecystokinin analogs for controlling appetite F. HOFFMANN-LA ROCHE AG (CH) 1988-12-28 EP disclosed
EP-0285061-A2 Cyclic peptides and their preparation F. HOFFMANN-LA ROCHE AG (CH) 1988-10-05 EP disclosed
EP-0277419-A2 Therapeutic somatostatin analogues THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1988-08-10 EP disclosed
US-4734400-A BRONCHODILATION WITHOUT CARDIOVASCULAR SIDE EFFECTS HOFFMANN-LA ROCHE INC. (US) 1988-03-29 US disclosed
EP-0099286-B1 COMPOUND CONTAINING A TRIPEPTIDE SEQUENCE OF THE THREONYL-LYSYL PROLINE-TYPE, OR SIMILAR, USEFUL AS AN ANTI-INFLAMMATORY, ANTI-ALLERGIC OR ANTALGESIC AGENT INSTITUT PASTEUR DE LILLE (FR) 1987-05-20 EP disclosed
EP-0214872-A2 Somatostatin analoge The Administrators of The Tulane Educational Fund (US) 1987-03-18 EP disclosed
US-4605641-A BRONCHODILATOR AGENTS HOFFMANN-LA ROCHE INC. (US) 1986-08-12 US disclosed
EP-0099286-A1 Compound containing a tripeptide sequence of the threonyl-lysyl proline-type, or similar, useful as an anti-inflammatory, anti-allergic or antalgesic agent INSTITUT PASTEUR DE LILLE (FR) 1984-01-25 EP disclosed
US-4146614-A TREATMENT OF SCHIZOPHRENIA STATE OF MICHIGAN (US) 1979-03-27 US disclosed
US-4127525-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368096-A1 Fused Heterobicyclic Antiviral Agents HAVCR2, HDGF, SLC10A1 PPARA 2191/4885PTPN1 2372/4885CDC25B 19/4885
US-20250074901-A1 NOVEL HETEROARYL COMPOUNDS H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP3A43, F12 PPARA 4477/4885PTPN1 1905/4885CDC25B 2498/4885
US-20240174680-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK20, CDK2AP2 PPARA 3679/4885PTPN1 2442/4885CDC25B 47/4885
US-12358951-B2 Cyclic peptide antibiotics NPPA, LNPEP, CLPP PPARA 455/4885PTPN1 652/4885CDC25B 2279/4885
US-12053459-B2 CDK2 inhibitors and methods of using the same CDK2, CDK20, CDK2AP2 PPARA 3115/4885PTPN1 2211/4885CDC25B 50/4885
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 PPARA 4500/4885PTPN1 912/4885CDC25B 2768/4885
US-12065445-B2 CDK2 inhibitors and methods of using the same CDK2, CDK20, CDK1 PPARA 3800/4885PTPN1 1669/4885CDC25B 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.