Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351617 | 0.90 | ITGB1 (0.53) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL194738 | 0.90 | ITGB1 (0.53) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL6352517 | 0.88 | ITGB1 (0.55) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL6351647 | 0.86 | CYP3A4 (0.52) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL11248915 | 0.85 | FKBP1A (0.57) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL11248907 | 0.85 | FKBP1A (0.57) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL11248906 | 0.85 | FKBP1A (0.57) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL6354036 | 0.85 | CYP3A4 (0.51) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL2177077 | 0.83 | DPP4 (0.57) | ALDH1A1POLBDPP4 | |
| SCHEMBL474918 | 0.83 | DPP4 (0.57) | ALDH1A1POLBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021216-A1 | BIOLOGICALLY ACTIVE N-ACYLPROLYLDIPEPTIDES HAVING ANTIAMNESTIC, ANTIHYPOXIC AND ANOREXIGENIC EFFECTS | RUSSIAN-AMERICAN INSTITUTE FOR NEW DRUG DEVELOPMENT (US) | 1993-10-28 | — | — | WO | disclosed |