Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018722 | 0.88 | PDE4D (0.42) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL25084227 | 0.87 | PDE4D (0.52) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL7564025 | 0.86 | BCHE (0.50) | PDE4DSLC6A2BCHEACHESSTR1 | |
| SCHEMBL7564019 | 0.86 | BCHE (0.50) | PDE4DSLC6A2BCHEACHESSTR1 | |
| SCHEMBL20107286 | 0.85 | PDE4D (0.44) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL7900265 | 0.83 | PDE4D (0.43) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL20107274 | 0.82 | PDE4D (0.43) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL20107390 | 0.82 | PDE4D (0.43) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL8330102 | 0.82 | PDE4D (0.43) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL14428904 | 0.80 | PDE4D (0.47) | PDE4DSLC6A2BCHEPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017032-A1 | TECHNIQUES AND INTERMEDIATES FOR PREPARING NON-PEPTIDE PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-09-02 | — | — | WO | disclosed |