Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545173 | 0.85 | PDE4D (0.48) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL7900265 | 0.82 | PDE4D (0.43) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL25084227 | 0.78 | PDE4D (0.52) | PDE4DSLC6A2CYP2C19PSEN1PSEN2 | |
| SCHEMBL31556088 | 0.76 | PDE4D (0.59) | PDE4DSLC6A2BCHEACHESSTR1 | |
| SCHEMBL16149060 | 0.74 | PDE4D (0.54) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL16149061 | 0.74 | PDE4D (0.54) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL16149062 | 0.74 | PDE4D (0.54) | PDE4DSLC6A2BCHEACHEPDPK1 | |
| SCHEMBL8647380 | 0.74 | PDE4D (0.54) | PDE4DSLC6A2BCHEACHECYP2C19 | |
| SCHEMBL8640912 | 0.74 | PDE4D (0.54) | PDE4DSLC6A2BCHEACHECYP2C19 | |
| SCHEMBL20725200 | 0.73 | PDE4D (0.50) | PDE4DSLC6A2BCHEACHEPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315502-A1 | C,O-SPIRO ARYL GLYCOSIDE COMPOUNDS, PREPARATION THEREFOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-05-02 | — | — | EP | disclosed |