Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545245 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL29566961 | 0.92 | MME (0.49) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL30011110 | 0.92 | ACE (0.56) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL30010902 | 0.92 | ACE (0.56) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL30010855 | 0.92 | ACE (0.56) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL30010989 | 0.92 | ACE (0.56) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL29714714 | 0.91 | FNTA (0.48) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL31469847 | 0.90 | MME (0.46) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL31720932 | 0.89 | ACE (0.51) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL29893864 | 0.89 | FOLH1 (0.58) | ALDH1A1MMEFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021211-A1 | AMIDES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS MENARINI S.A. (ES) | 1993-10-28 | — | — | WO | disclosed |