Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544288 | 0.92 | CXCR3 (0.41) | CXCR3OPRM1OPRD1OPRK1FNTA | |
| SCHEMBL9544378 | 0.88 | FNTA (0.46) | FNTAFNTBHDAC8 | |
| SCHEMBL9544383 | 0.88 | FNTA (0.46) | FNTAFNTBHDAC8 | |
| SCHEMBL9544910 | 0.85 | HDAC3 (0.48) | CXCR3OPRM1OPRD1OPRK1HDAC8 | |
| SCHEMBL9544919 | 0.85 | HDAC3 (0.48) | CXCR3OPRM1OPRD1OPRK1HDAC8 | |
| SCHEMBL9545046 | 0.85 | FNTA (0.41) | CXCR3OPRM1OPRD1OPRK1FNTA | |
| SCHEMBL9545049 | 0.85 | FNTA (0.41) | CXCR3OPRM1OPRD1OPRK1FNTA | |
| SCHEMBL9545323 | 0.82 | CXCR3 (0.41) | CXCR3OPRM1OPRD1OPRK1FNTA | |
| SCHEMBL9544283 | 0.82 | KMT2A (0.43) | CXCR3OPRM1OPRD1OPRK1ATM | |
| SCHEMBL9545327 | 0.82 | CXCR3 (0.41) | CXCR3OPRM1OPRD1OPRK1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |