Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 13/20 | 0.46 |
| ▸ | HTR1D | P28221 | 11/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545605 | 0.92 | HTR1B (0.46) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8979722 | 0.89 | HTR1B (0.51) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8886182 | 0.83 | HTR6 (0.49) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8914055 | 0.80 | HTR1B (0.52) | HTR1BHTR1DHTR1AHTR6HTR2A | |
| SCHEMBL8979702 | 0.80 | DAGLA (0.49) | HTR1BHTR1DHTR1AHTR6DAGLA | |
| SCHEMBL8915516 | 0.79 | HTR1B (0.45) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8915512 | 0.79 | HTR1B (0.45) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8979679 | 0.79 | HTR1B (0.53) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8913746 | 0.78 | HTR1B (0.49) | HTR1BHTR1DHTR1AHTR6HTR2A | |
| SCHEMBL8915703 | 0.78 | HTR1B (0.49) | HTR1BHTR1DHTR1AHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021178-A1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS | PFIZER LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |