Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 13/20 | 0.82 |
| ▸ | PLK4 | O00444 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | PAK4 | O96013 | 1/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | PRKCG | P05129 | 1/20 | 0.59 |
| ▸ | PRKCB | P05771 | 1/20 | 0.59 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | LYN | P07948 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544996 | 1.00 | MYLK (0.82) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL9544980 | 1.00 | MYLK (0.82) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL9544717 | 1.00 | MYLK (0.82) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL9544970 | 0.90 | MYLK (1.00) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL9545348 | 0.90 | MYLK (1.00) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL9544986 | 0.89 | MYLK (0.80) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL9544887 | 0.89 | MYLK (0.80) | MYLKPLK4AURKAPDPK1JAK2 | |
| SCHEMBL8112505 | 0.88 | MYLK (0.76) | MYLKPRKACAKDRPRKD1 | |
| SCHEMBL8119651 | 0.88 | MYLK (0.76) | MYLKPRKACAKDRPRKD1 | |
| SCHEMBL9544954 | 0.86 | MYLK (1.00) | MYLKPLK4AURKAPDPK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |