Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GNPAT | O15228 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93990 | 0.96 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL93989 | 0.96 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL93988 | 0.96 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL27496141 | 0.90 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL931029 | 0.85 | KDM4E (0.67) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12729510 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL25509507 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| Acetylcysteine SCHEMBL27610444 | 0.83 | MAPT (0.91) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL3027984 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL10070143 | 0.82 | KDM4E (0.50) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023425-A1 | METAL CHELATING PEPTIDE | THE ONTARIO CANCER INSTITUTE (CA) | 1993-11-25 | — | — | WO | disclosed |