Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | THPO | P40225 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GNPAT | O15228 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93988 | 1.00 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL93989 | 1.00 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| Hydrazine SCHEMBL9545541 | 0.96 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL27496141 | 0.94 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL931029 | 0.89 | KDM4E (0.67) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12729510 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL25509507 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL3027984 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14111193 | 0.84 | KDM4E (0.54) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7713736 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260083127-A1 | Thiolactone-Derived Compounds for Generating Nitric Oxide and Methods of Forming the Same | STERILE STATE, LLC (US) | 2026-03-26 | — | — | US | claimed |
| EP-4622957-A1 | THIOLACTONE-DERIVED COMPOUNDS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME | Sterile State LLC (US) | 2025-10-01 | — | — | EP | claimed |
| WO-2025080553-A1 | NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2025-04-17 | — | — | WO | claimed |
| EP-4404944-A1 | NITRIC OXIDE RELEASING POLYSILOXANES AND METHODS FOR MAKING AND USING THE SAME | University of Georgia Research Foundation, Inc. (US) | 2024-07-31 | — | — | EP | claimed |
| WO-2024112667-A1 | THIOLACTONE-DERIVED COMPOUNDS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME | STERILE STATE, LLC (US) | 2024-05-30 | — | — | WO | claimed |
| US-20240147990-A1 | Delivery Particles Based On Amine-Thiol-Ene Conjugates and Derivatives | ENCAPSYS, LLC (US) | 2024-05-09 | — | — | US | claimed |
| US-11975499-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-05-07 | — | — | US | claimed |
| WO-2024086501-A1 | DELIVERY PARTICLES BASED ON AMINE-THIOL-ENE CONJUGATES AND DERIVATIVES | ENCAPSYS, LLC (US) | 2024-04-25 | — | — | WO | claimed |
| US-20240131231-A1 | NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF | NATIONAL INSTITUTES OF HEALTH | 2024-04-25 | — | — | US | claimed |
| EP-4288123-A1 | NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF | University of Georgia Research Foundation, Inc. (US) | 2023-12-13 | — | — | EP | claimed |
| US-4708965-A | Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives | MORGAN LEE R (US) | 1987-11-24 | — | — | US | claimed |
| US-4686284-A | Production of monomeric human γ-interferon | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-11 | — | — | US | claimed |
| EP-0080879-B1 | PHARMACEUTICAL COMPOSITION CONTAINING INTERFERON IN STABLE STATE | SUNSTAR KABUSHIKI KAISHA (JP) | 1986-10-01 | — | — | EP | claimed |
| EP-0057140-B1 | THIOLATED POLYPEPTIDIC COMPOUND FROM A TETANIC TOXIN FRAGMENT, PROCESS FOR ITS PRODUCTION AND ITS APPLICATIONS | INSTITUT PASTEUR (FR) | 1985-07-17 | — | — | EP | claimed |
| EP-0136694-A2 | Production of monomeric human gamma-interferon | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | claimed |
| EP-0030496-B1 | THIOLATED POLYPEPTIDIC COMPOUND COMING FROM A FRAGMENT OF TETANIC TOXINE, PROCESS FOR OBTAINING IT AND ITS APPLICATIONS | INSTITUT PASTEUR (FR) | 1983-07-13 | — | — | EP | claimed |
| EP-0080879-A2 | Pharmaceutical composition containing interferon in stable state | SUNSTAR KABUSHIKI KAISHA (JP) | 1983-06-08 | — | — | EP | claimed |
| EP-0057140-A2 | Thiolated polypeptidic compound from a tetanic toxin fragment, process for its production and its applications | INSTITUT PASTEUR (FR) | 1982-08-04 | — | — | EP | claimed |
| EP-0030496-A1 | Thiolated polypeptidic compound coming from a fragment of tetanic toxine, process for obtaining it and its applications | INSTITUT PASTEUR (FR) | 1981-06-17 | — | — | EP | claimed |
| US-3934004-A | Stain resistant anti-perspirant composition | ORREN LEONARD J | 1976-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240131231-A1 | NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF | NOS2, NOS1, NOS3 | SMN1; SMN2 2667/4885KDM4E 4514/4885MAPT 4697/4885 |
| US-20260083127-A1 | Thiolactone-Derived Compounds for Generating Nitric Oxide and Methods of Forming the Same | NOS1, NOS3, NOS2 | SMN1; SMN2 1657/4885KDM4E 1890/4885MAPT 3219/4885 |
| US-20240147990-A1 | Delivery Particles Based On Amine-Thiol-Ene Conjugates and Derivatives | ACR, MMAB, UBE3C | SMN1; SMN2 735/4885KDM4E 76/4885MAPT 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.