Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997760 | 0.85 | TSHR (0.39) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL5014835 | 0.81 | TSHR (0.32) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL28216886 | 0.81 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL672062 | 0.80 | TSHR (0.50) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL23494319 | 0.78 | TSHR (0.50) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL991364 | 0.78 | TSHR (0.45) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL27718796 | 0.77 | TSHR (0.44) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL27997945 | 0.75 | TSHR (0.37) | TSHR | |
| SCHEMBL6557557 | 0.74 | TSHR (0.45) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL7074331 | 0.74 | TSHR (0.45) | TSHRALDH1A1TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | claimed |