SCHEMBL5014835

SCHEMBL5014835

C=CC(=O)OC(O)CC[SiH2]O[SiH3]

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014814 0.82 TSHR (0.33) TSHRALDH1A1TP53CYP3A4HIF1A
SCHEMBL9546119 0.81 TSHR (0.38) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL26503 0.76 TSHR (0.44) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL11233280 0.75 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL5014893 0.75 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL27143080 0.74 TSHR (0.42) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL2119381 0.74 TSHR (0.45) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL28264652 0.74 TSHR (0.38) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL709411 0.72 TSHR (0.36) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL9333707 0.71 TSHR (0.40) TSHRALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed