Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | F7 | P08709 | 6/20 | 0.48 |
| ▸ | F3 | P13726 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | FABP4 | P15090 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546156 | 1.00 | PPARG (0.48) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL9546183 | 0.88 | EPHX2 (0.42) | ALDH1A1OXER1 | |
| SCHEMBL10606550 | 0.84 | PPARG (0.50) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL10608208 | 0.84 | PPARG (0.50) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL10622161 | 0.77 | PPARG (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL10622158 | 0.77 | PPARG (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL24854676 | 0.71 | PPARG (0.51) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL31213146 | 0.70 | PPARG (0.89) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL9931678 | 0.70 | PPARG (0.96) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL15296 | 0.70 | PPARG (0.96) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |