Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 5/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | F7 | P08709 | 4/20 | 0.52 |
| ▸ | F3 | P13726 | 4/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622158 | 1.00 | PPARG (0.55) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10608164 | 0.87 | NFKB1 (0.49) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10608167 | 0.87 | NFKB1 (0.49) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10772968 | 0.87 | NFKB1 (0.49) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10772965 | 0.87 | NFKB1 (0.49) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10603475 | 0.87 | NFKB1 (0.49) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10603470 | 0.87 | NFKB1 (0.49) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10619862 | 0.87 | TRPA1 (0.57) | PPARGALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10619859 | 0.87 | TRPA1 (0.57) | PPARGALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14344308 | 0.87 | TRPA1 (0.57) | PPARGALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| EP-0106576-A2 | Novel 5-membered cyclic compounds, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |