Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546191 | 1.00 | PTGER4 (0.31) | PTGER4PPARGPPARAITGB1ITGA4 | |
| SCHEMBL9546152 | 0.88 | LTB4R (0.34) | PTGER4ITGB1ITGA4 | |
| SCHEMBL9546149 | 0.88 | LTB4R (0.34) | PTGER4ITGB1ITGA4 | |
| SCHEMBL9546169 | 0.86 | PTGER4 (0.32) | PTGER4 | |
| SCHEMBL9546171 | 0.86 | PTGER4 (0.32) | PTGER4 | |
| SCHEMBL9546239 | 0.84 | NQO2 (0.32) | PPARGPPARA | |
| SCHEMBL9546291 | 0.84 | ITGB1 (0.32) | PTGER4PPARGPPARAITGB1ITGA4 | |
| SCHEMBL9546283 | 0.84 | ITGB1 (0.32) | PTGER4PPARGPPARAITGB1ITGA4 | |
| SCHEMBL9546162 | 0.84 | PPARG (0.31) | PTGER4PPARGPPARA | |
| SCHEMBL9546164 | 0.84 | PPARG (0.31) | PTGER4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |