Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237060 | 0.90 | — | — | |
| SCHEMBL4621925 | 0.87 | CHRM2 (0.37) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL14141163 | 0.84 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL10449210 | 0.84 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL6653691 | 0.84 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL4648551 | 0.80 | PPM1D (0.32) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL7334201 | 0.79 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL2642444 | 0.78 | — | — | |
| SCHEMBL880204 | 0.77 | — | — | |
| SCHEMBL2325790 | 0.75 | CHRM2 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |