⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237060 | 0.86 | — | — | |
| SCHEMBL28115386 | 0.84 | TSHR (0.35) | — | |
| SCHEMBL4283399 | 0.84 | CHRM2 (0.33) | — | |
| SCHEMBL7640695 | 0.84 | TSHR (0.35) | — | |
| SCHEMBL28114860 | 0.84 | TSHR (0.35) | — | |
| SCHEMBL3672565 | 0.83 | CHRM2 (0.33) | — | |
| SCHEMBL10778204 | 0.81 | CHRM2 (0.42) | — | |
| SCHEMBL10929532 | 0.81 | CHRM2 (0.42) | — | |
| SCHEMBL3678402 | 0.81 | EPHX1 (0.34) | — | |
| SCHEMBL3678399 | 0.81 | EPHX1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976230-A | A method of dolasetron mesilate key intermediate is prepared based on graphene activation | 东莞市联洲知识产权运营管理有限公司 | 2018-12-11 | — | — | CN | claimed |
| CN-105566840-A | Method for preparing acrylonitrile-butadiene-styrene dispersoid | WANG JINMING | 2016-05-11 | — | — | CN | claimed |
| CN-108976230-A | A method of dolasetron mesilate key intermediate is prepared based on graphene activation | 东莞市联洲知识产权运营管理有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-108976230-A | A method of dolasetron mesilate key intermediate is prepared based on graphene activation | 东莞市联洲知识产权运营管理有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-105566840-A | Method for preparing acrylonitrile-butadiene-styrene dispersoid | WANG JINMING | 2016-05-11 | — | — | CN | disclosed |
| US-8809264-B2 | Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8361958-B2 | Oximyl HCV serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2433941-A1 | Process for isolating the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | Bristol-Myers Squibb Company (US) | 2012-03-28 | — | — | EP | disclosed |
| US-8101567-B2 | Heteroaryl-containing tripeptide HCV serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-7723423-B2 | Gas-barrier resin composition | CRYOVAC, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7635683-B2 | Quinoxalinyl tripeptide hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2009-12-22 | — | — | US | disclosed |
| US-20070299078-A1 | Quinoxalinyl Macrocyclic Hepatitis C Virus Serine Protease Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2007-12-27 | — | — | US | disclosed |
| US-7285598-B2 | Polymer and process for producing the same | KURARAY CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20070093599-A1 | Gas-barrier resin composition | CRYOVAC, INC. (US) | 2007-04-26 | — | — | US | disclosed |
| US-20070021556-A1 | Gas-barrier resin composition | KURARAY CO. LTD. (JP) | 2007-01-25 | — | — | US | disclosed |
| EP-1746131-A2 | Gas-barrier resin composition | Cryovac, Inc. (US) | 2007-01-24 | — | — | EP | disclosed |
| US-20060149009-A1 | Produced by ring-opening, in the presence of a metal alkylidene complex comprising a ligand with an imidazolidine structure, a cyclic olefin comprising at least one cyclic olefin further comprising a hydroxy group or a functional group that can be converted into a hydroxy group, and hydrogenating | KURARAY CO., LTD. (JP) | 2006-07-06 | — | — | US | disclosed |
| US-6559241-B2 | Process for producing a hydrogenated polymer | KURARAY CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |
| US-20020137854-A1 | Process for producing a hydrogenated polymer | KURARAY CO. LTD. (JP) | 2002-09-26 | — | — | US | disclosed |
| EP-1241189-A1 | Process for producing a hydrogenated polymer | KURARAY CO., LTD. (JP) | 2002-09-18 | — | — | EP | disclosed |