⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5641486 | 0.80 | — | — | |
| SCHEMBL9143007 | 0.78 | — | — | |
| SCHEMBL8329971 | 0.76 | — | — | |
| SCHEMBL209980 | 0.73 | — | — | |
| SCHEMBL23346129 | 0.70 | — | — | |
| SCHEMBL18279844 | 0.59 | — | — | |
| SCHEMBL214176 | 0.58 | — | — | |
| SCHEMBL583879 | 0.57 | HTR6 (0.56) | — | |
| SCHEMBL127850 | 0.57 | HTR6 (0.56) | — | |
| SCHEMBL22216666 | 0.55 | HTR6 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| EP-0150461-B1 | SULFUR CONTAINING 6-KETOPROSTAGLANDINES | MERCK PATENT GmbH (DE) | 1988-03-30 | — | — | EP | disclosed |
| US-4733011-A | ULTRAVIOLET RADIATION FOR DECYCLIZATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-22 | — | — | US | disclosed |
| US-4680288-A | Sulfur-containing 6-ketoprostaglandins | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-07-14 | — | — | US | disclosed |
| EP-0150461-A2 | Sulfur containing 6-Ketoprostaglandines | MERCK PATENT GmbH (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0043446-B1 | INTERMEDIATES OF 13-THIA-PROSTAGLANDIN, THEIR PREPARATION AND APPLICATION TO THE SYNTHESIS OF 13-THIA-PROSTAGLANDIN DERIVATIVES | MERCK PATENT GmbH (DE) | 1984-02-22 | — | — | EP | disclosed |
| EP-0084775-A1 | 13-Thia-prostacyclines | MERCK PATENT GmbH (DE) | 1983-08-03 | — | — | EP | disclosed |
| US-4309441-A | HYPOTENSIVE AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-01-05 | — | — | US | disclosed |
| US-4210651-A | Thiaprostaglandins | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-07-01 | — | — | US | disclosed |
| US-4180672-A | 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom | TEIJIN LIMITED (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4080458-A | HYPOTENSIVE AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-03-21 | — | — | US | disclosed |
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |