Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546449 | 1.00 | PTGS1 (0.56) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL30776613 | 1.00 | PTGS1 (0.56) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL11015452 | 0.97 | PTGS1 (0.53) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL9176689 | 0.87 | HTR2A (0.53) | AKR1C3AKR1C2CYP1A2LMNAMAPT | |
| SCHEMBL11139966 | 0.86 | PTGS1 (0.53) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL13484112 | 0.85 | PTGS1 (0.54) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL11079473 | 0.83 | CYP1A2 (0.58) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL8338309 | 0.83 | CYP1A2 (0.58) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL8683396 | 0.83 | AKR1C3 (0.53) | PTGS1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL27512042 | 0.83 | CYP1A2 (0.54) | PTGS1AKR1C3AKR1C2CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586115-A | Preparation method of naproxen | 黑龙江立科新材料有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-117586115-A | Preparation method of naproxen | 黑龙江立科新材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586115-A | Preparation method of naproxen | 黑龙江立科新材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-110724032-A | Method for preparing alcohol compound by hydrogenation reduction of ketone and aldehyde | 大连理工大学 | 2020-01-24 | — | — | CN | disclosed |
| WO-1993023547-A1 | ENZYMATIC PROCESS FOR PRODUCTION OF S-6-METHOXY-α-METHYL-2-NAPHTHALENEACETIC ACID | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1993-11-25 | — | — | WO | disclosed |