Bromobenzene

Bromobenzene

SCHEMBL9546448

Brc1ccccc1.FC(F)(F)OC(F)(F)F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TDP1 Q9NUW8 1/20 0.58
MAPK1 P28482 1/20 0.42
TSHR P16473 1/20 0.38
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAOB P27338 3/20 0.32
HTR2A P28223 1/20 0.32
KIF11 P52732 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA5A P35218 2/20 0.31
CA9 Q16790 2/20 0.31
MAOA P21397 2/20 0.31
MAPT P10636 2/20 0.31
CES1 P23141 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7091889 0.78 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1TSHRIDO1
Bromobenzene SCHEMBL537562 0.76 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1TSHRCYP2A6
Bromobenzene SCHEMBL1331681 0.76
Bromobenzene SCHEMBL1332317 0.76
Bromobenzene SCHEMBL2158200 0.76
Bromobenzene SCHEMBL20537325 0.76 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1TSHRCYP2A6
Bromobenzene SCHEMBL1542 0.76
Bromobenzene SCHEMBL1331176 0.76
Benzene SCHEMBL11528079 0.76 ALDH1A1 (0.32) ALDH1A1TSHR
Bromobenzene SCHEMBL15050431 0.74 ALDH1A1 (0.58) ALDH1A1TDP1MAPK1TSHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993024600-A1 OXIDATION-RESISTANT CYCLOPHOSPHAZENE FLUID INCLUDING TRIARYLPHOSPHINE OR PHOSPHINE OXIDE THE DOW CHEMICAL COMPANY (US) 1993-12-09 WO disclosed
US-5194652-A High temperature lubricants, hydraulic fluids; jet aircraft, turbines, diesel engines THE DOW CHEMICAL COMPANY (US) 1993-03-16 US disclosed
US-4194899-A HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS ELI LILLY AND COMPANY (US) 1980-03-25 US disclosed
US-4110099-A INHIBITOR FOR INTERNODEL GROWTH OF PLANTS ELI LILLY AND COMPANY (US) 1978-08-29 US disclosed
US-4043791-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1977-08-23 US disclosed
US-RE29367-E HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL ELI LILLY AND COMPANY (US) 1977-08-23 US disclosed
US-4002628-A HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS ELI LILLY AND COMPANY (US) 1977-01-11 US disclosed
US-3992446-A ANTIPROTOZOAL ACTIVITY, PARTICULARLY AGAINST COCCIDIOSIS AND MALARIA AMERICAN CYANAMID COMPANY (US) 1976-11-16 US disclosed
US-3967949-A Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents ELI LILLY AND COMPANY (US) 1976-07-06 US disclosed
US-3941825-A ANTIPROTOZOA INTERMEDIATES AMERICAN CYANAMID COMPANY (US) 1976-03-02 US disclosed