Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546505 | 1.00 | NPSR1 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL13968423 | 0.94 | NPSR1 (0.43) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL5142842 | 0.93 | KLK5 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL7283432 | 0.93 | KLK5 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL6305846 | 0.93 | KLK5 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL6446803 | 0.93 | KLK5 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL7796450 | 0.93 | KLK5 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL7398818 | 0.93 | KLK5 (0.47) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL9546501 | 0.92 | KLK5 (0.43) | NPSR1LMNAHPGDHTTALDH1A1 | |
| SCHEMBL9546495 | 0.92 | KLK5 (0.43) | NPSR1LMNAHPGDHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |