Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219007 | 0.92 | AR (0.51) | ARKCNH2SRD5A1SRD5A2 | |
| SCHEMBL14223332 | 0.87 | AR (0.54) | ARKCNH2SRD5A2 | |
| SCHEMBL8902469 | 0.86 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL2639491 | 0.86 | AR (0.53) | ARKCNH2SRD5A2 | |
| SCHEMBL4803550 | 0.86 | AR (0.53) | ARKCNH2SRD5A2 | |
| SCHEMBL8909725 | 0.84 | AR (0.64) | ARKCNH2SRD5A2 | |
| SCHEMBL8904185 | 0.83 | AR (0.61) | ARKCNH2SRD5A2 | |
| SCHEMBL8904183 | 0.83 | AR (0.61) | ARKCNH2SRD5A2 | |
| SCHEMBL14223683 | 0.82 | AR (0.57) | ARKCNH2SRD5A2 | |
| SCHEMBL4799349 | 0.81 | AR (0.56) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023038-A1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |