Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 7/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546747 | 1.00 | P2RX7 (0.40) | P2RX7KMT2ACTSSAPPPSEN1 | |
| SCHEMBL9546723 | 1.00 | P2RX7 (0.40) | P2RX7KMT2ACTSSAPPPSEN1 | |
| SCHEMBL9546434 | 0.94 | KMT2A (0.41) | P2RX7KMT2ACTSSAPPPSEN1 | |
| SCHEMBL9546429 | 0.94 | KMT2A (0.41) | P2RX7KMT2ACTSSAPPPSEN1 | |
| SCHEMBL9546437 | 0.94 | KMT2A (0.41) | P2RX7KMT2ACTSSAPPPSEN1 | |
| SCHEMBL9546698 | 0.91 | KMT2A (0.42) | KMT2AAPPPSEN1PSEN2APH1B | |
| SCHEMBL9546707 | 0.91 | KMT2A (0.42) | KMT2AAPPPSEN1PSEN2APH1B | |
| SCHEMBL9546715 | 0.91 | KMT2A (0.42) | KMT2AAPPPSEN1PSEN2APH1B | |
| SCHEMBL9546754 | 0.89 | BACE1 (0.41) | KMT2AAPPPSEN1PSEN2APH1B | |
| SCHEMBL9546732 | 0.89 | BACE1 (0.41) | KMT2AAPPPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |