Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546774 | 1.00 | KMT2A (0.53) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL19981944 | 0.86 | KMT2A (0.55) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL2775499 | 0.86 | KMT2A (0.55) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL19981901 | 0.86 | KMT2A (0.55) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL9546610 | 0.86 | KMT2A (0.53) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL9546846 | 0.85 | KMT2A (0.54) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL9102890 | 0.84 | KMT2A (0.53) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL9102898 | 0.84 | KMT2A (0.53) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL1706224 | 0.83 | CTSK (0.64) | KMT2AMEN1CTSKCTSLCTSB | |
| SCHEMBL9102129 | 0.83 | CTSK (0.60) | KMT2AMEN1CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |