Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546879 | 1.00 | SRD5A1 (0.56) | SRD5A1CYP2C19ALDH1A1NR3C1MAPK1 | |
| SCHEMBL9546868 | 0.83 | SRD5A1 (0.56) | SRD5A1CYP2C19SRD5A2CYP19A1 | |
| SCHEMBL9546870 | 0.83 | SRD5A1 (0.56) | SRD5A1CYP2C19SRD5A2CYP19A1 | |
| SCHEMBL29059721 | 0.82 | SRD5A1 (0.64) | SRD5A1CYP2C19ALDH1A1NR3C1MAPK1 | |
| SCHEMBL8927022 | 0.80 | SRD5A1 (0.51) | SRD5A1CYP2C19SRD5A2 | |
| SCHEMBL7613570 | 0.78 | SRD5A1 (0.67) | SRD5A1NR3C1MAPK1SIGMAR1SERPINA6 | |
| SCHEMBL7613573 | 0.78 | SRD5A1 (0.67) | SRD5A1NR3C1MAPK1SIGMAR1SERPINA6 | |
| SCHEMBL11416876 | 0.78 | SRD5A1 (0.64) | SRD5A1CYP2C19SERPINA6SRD5A2SHBG | |
| SCHEMBL9022075 | 0.78 | SRD5A1 (0.64) | SRD5A1CYP2C19SERPINA6SRD5A2SHBG | |
| SCHEMBL5218487 | 0.78 | SRD5A1 (0.64) | SRD5A1CYP2C19SERPINA6SRD5A2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023039-A1 | SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |