Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 3/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.46 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | FGF1 | P05230 | 3/20 | 0.41 |
| ▸ | FGF2 | P09038 | 3/20 | 0.41 |
| ▸ | VEGFA | P15692 | 3/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113797 | 0.98 | MAPK1 (0.52) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL23113799 | 0.98 | MAPK1 (0.52) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL18733215 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL17300176 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL18333048 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL15508089 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL12819629 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL18733408 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL16079127 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 | |
| SCHEMBL18030218 | 0.93 | MAPK1 (0.44) | MAPK1GBA1GJB2LGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023570-A1 | OLIGONUCLEOTIDES HAVING CONJUGATES ATTACHED AT THE 2'-POSITION OF THE SUGAR MOIETY | PHARMAGENICS, INC. (US) | 1993-11-25 | — | — | WO | disclosed |