Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9547160 | 0.78 | TSHR (0.39) | TSHR | |
| Bromide SCHEMBL9547319 | 0.76 | CHRM5 (0.50) | TSHR | |
| Bromide SCHEMBL9547167 | 0.74 | SELP (0.35) | MCL1 | |
| SCHEMBL13964932 | 0.71 | HTT (0.56) | — | |
| SCHEMBL26619200 | 0.71 | HTT (0.56) | — | |
| Hydrochloric Acid SCHEMBL25391260 | 0.69 | HTT (0.54) | — | |
| SCHEMBL28228540 | 0.69 | DNM1 (0.37) | TSHR | |
| SCHEMBL3106710 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27754960 | 0.67 | DNM1 (0.36) | TSHR | |
| SCHEMBL9547219 | 0.67 | MCL1 (0.39) | MCL1TSHRSLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |