Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547286 | 0.71 | MEN1 (0.41) | MEN1KMT2AGAAKDM1ACACNA2D1 | |
| SCHEMBL9547266 | 0.69 | KDM1A (0.44) | MEN1KMT2AGAAKDM1ACACNA2D1 | |
| SCHEMBL9547253 | 0.62 | KDM1A (0.42) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL4939495 | 0.59 | MEN1 (0.67) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL9547317 | 0.59 | TOP2A (0.60) | MEN1KMT2AKDM1APOLBRAD52 | |
| SCHEMBL5404455 | 0.58 | KMT2A (0.48) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL28241436 | 0.58 | KDM4E (0.55) | KMT2AGAACACNA2D1POLBRAD52 | |
| SCHEMBL13692586 | 0.58 | KDM1A (0.58) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL4658830 | 0.58 | KDM1A (0.67) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL23630584 | 0.57 | KDM1A (0.78) | MEN1KMT2AGAAKDM1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023049-A1 | 3-(9-ACRIDINYLAMINO)-5-HYDROXYMETHYLANILINE DERIVATIVES AS ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-11-25 | — | — | WO | claimed |