Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465346 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10LMNASMN1; SMN2POLB | |
| SCHEMBL7191810 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10HPGDLMNAPOLB | |
| SCHEMBL10403880 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10LMNASMN1; SMN2POLB | |
| SCHEMBL10971800 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HSD17B10LMNASMN1; SMN2KMT2A | |
| SCHEMBL11031214 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HSD17B10LMNASMN1; SMN2POLB | |
| SCHEMBL10974031 | 0.77 | ALDH1A1 (0.75) | ALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL10969206 | 0.74 | ALDH1A1 (0.69) | ALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL8316978 | 0.74 | — | — | |
| SCHEMBL8445215 | 0.74 | — | — | |
| SCHEMBL10970753 | 0.74 | ALDH1A1 (0.69) | ALDH1A1HSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084173-A | 1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid derivative and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-23 | — | — | CN | disclosed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |