Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL5527 | 0.89 | — | — | |
| Ethylene SCHEMBL10561806 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1TSHR | |
| Ethylene SCHEMBL10382764 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1TSHR | |
| Ethylene SCHEMBL994924 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1TSHR | |
| Acetic Acid SCHEMBL7580002 | 0.87 | CA1 (0.42) | ALDH1A1CA1HSD17B10TDP1TSHR | |
| Acetic Acid SCHEMBL27565397 | 0.87 | CA1 (0.42) | ALDH1A1CA1HSD17B10TDP1TSHR | |
| Ethylene SCHEMBL7644453 | 0.87 | — | — | |
| Ethylene SCHEMBL6072796 | 0.87 | — | — | |
| Ethylene SCHEMBL29631732 | 0.87 | — | — | |
| Ethylene SCHEMBL9815378 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5178649-A | — | — | None | — | — | JP | disclosed |
| JP-H05178649-A | COMPOSITION OF BOTTOM SPRAYING MATERIAL AND TECHNIQUE FOR FORMING EXTERNAL WALL ON SURFACE OF BODY | FUJIKAWA KENZAI KOGYO KK | 1993-07-20 | — | — | JP | disclosed |