SCHEMBL9547731

SCHEMBL9547731

S=C=Nc1ccc(Cc2ccc(N=C=S)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 2/20 0.74
CYP3A4 P08684 2/20 0.60
TSHR P16473 2/20 0.60
MIF P14174 3/20 0.54
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HSD17B10 Q99714 1/20 0.44
CYP1A2 P05177 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
SLC22A2 O15244 1/20 0.38
CHRM1 P11229 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TRPA1 O75762 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1193625 1.00 P2RY6 (0.74) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL5954394 0.91 MIF (0.64) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL11697898 0.89 CYP3A4 (0.80) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL14108667 0.89 P2RY6 (0.61) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL14107953 0.89 P2RY6 (0.61) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL17274363 0.88 P2RY6 (0.59) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL1853024 0.85 P2RY6 (1.00) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL9547715 0.85 P2RY6 (1.00) P2RY6CYP3A4TSHRMIFCA1
Bitoscanate SCHEMBL157128 0.84 MIF (0.72) P2RY6CYP3A4TSHRMIFCA1
SCHEMBL13633309 0.81 P2RY6 (0.68) P2RY6CYP3A4TSHRMIFCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed